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The effect of endocrine disease on lipid metabolism
/content/chapter/10.22233/9781910443866.chap7
The effect of endocrine disease on lipid metabolism
- Author: Panagiotis G. Xenoulis
- From: BSAVA Manual of Canine and Feline Endocrinology
- Item: Chapter 7, pp 44 - 53
- DOI: 10.22233/9781910443866.7
- Copyright: © 2023 British Small Animal Veterinary Association
- Publication Date: August 2023
Abstract
This chapter provides an overview of lipid metabolism and details the relationship between endocrine diseases and lipid metabolism in dogs and cats. It discusses the expanding knowledge of hyperlipidemia and its emerging importance as a clinical condition. The roles of various enzymes and hormones in lipid metabolism are explained. The consequences of hyperlipidemia are also covered. The diagnostic approach to hyperlipidemia in dogs and cats is outlined along with treatment options including dietary management and lipid-lowering drugs.
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Figures
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7.1
The basics of lipoprotein metabolism in dogs and cats. Cholesteryl ester transfer protein does not exist in dogs and in its absence HDL2 is transformed into HDL1. apo = apolipoprotein; HDL = high-density lipoprotein; LDL = low-density lipoprotein; VLDL = very-low-density lipoprotein. Drawn by S.J. Elmhurst BA Hons (www.livingart.org.uk) and reproduced with her permission. © 2023 British Small Animal Veterinary Association
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7.1
The basics of lipoprotein metabolism in dogs and cats. Cholesteryl ester transfer protein does not exist in dogs and in its absence HDL2 is transformed into HDL1. apo = apolipoprotein; HDL = high-density lipoprotein; LDL = low-density lipoprotein; VLDL = very-low-density lipoprotein. Drawn by S.J. Elmhurst BA Hons (www.livingart.org.uk) and reproduced with her permission.
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7.2
Lipaemia. (a) Serum samples with reference interval triglyceride concentrations are clear. (b) Lactescent serum indicates severely increased serum triglyceride concentrations. © 2023 British Small Animal Veterinary Association
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7.2
Lipaemia. (a) Serum samples with reference interval triglyceride concentrations are clear. (b) Lactescent serum indicates severely increased serum triglyceride concentrations.
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7.3
Algorithm showing the basic steps in the diagnostic approach in dogs and cats with hyperlipidaemia. CBC = complete blood count; LDDS = low-dose dexamethasone suppression; PU/PD = polyuria and polydipsia; T4 = thyroxine; TSH = thyroid-stimulating hormone; UPCR = urine protein:creatinine. © 2023 British Small Animal Veterinary Association
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7.3
Algorithm showing the basic steps in the diagnostic approach in dogs and cats with hyperlipidaemia. CBC = complete blood count; LDDS = low-dose dexamethasone suppression; PU/PD = polyuria and polydipsia; T4 = thyroxine; TSH = thyroid-stimulating hormone; UPCR = urine protein:creatinine.