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Feline hypercortisolism

image of Feline hypercortisolism
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Abstract

This chapter focuses on feline hypercortisolism, a condition characterized by excess production of cortisol in cats, covering its causes, clinical features, diagnosis and treatment options. It provides information on differentiating tests used to determine whether hypercortisolism is pituitary- or adrenal-dependent. Medical and surgical approaches to therapy are discussed. The prognosis for cats with untreated hypercortisolism is poor, but treatment options can provide prolonged survival and may lead to diabetic remission in cats with concurrent diabetes mellitus.

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Figures

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30.2 Uncontrolled hypercortisolism in a cat. (a) Note the alopecia, thin inelastic skin and large wound. (b) Tail of the same cat – note the partial alopecia.
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30.5 Right lateral view of a cat with an adrenal tumour. An abnormal circular structure (arrowed) can be seen cranial to the right kidney (arrowhead); it is a large adrenal tumour.
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30.7 The same cat as in Figure 30.2 after 2 months of trilostane therapy. Note the healing of the skin wound and partial regrowth of hair. The required insulin dose for the concurrent diabetes mellitus also decreased when trilostane therapy was initiated.
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