The increasing recognition of systemic hypertension as a cause of clinical signs and a complication of common medical conditions makes blood pressure measurement an important diagnostic test in clinical veterinary medicine. Reliable measurement techniques, accurate assessment of results and effective therapeutic choices are needed to manage hypertension in dogs and cats successfully. Direct blood pressure measurement (i.e. intra-arterial needle or catheter) is accurate but technically challenging in dogs and cats. Measurement of blood pressure using non-invasive methods requires less technical skill but results may be inaccurate if careful attention is not paid to technique. The advantages enjoyed by physicians in measuring human blood pressure (i.e. generally cylinder-shaped appendages that easily allow cuff placement at the level of the heart; heart rates usually <150 beats/minute; lack of panting; and patient familiarity with the procedure) are not routinely present in conscious pet dogs and cats. Patient anxiety or excitement due to unfamiliarity with the procedure, rapid heart rates and the requirement that the patient remain motionless in what may be an abnormal position may lead to results that are inconsistent and difficult to interpret. These problems may be lessened, if not completely ameliorated, by excellent and consistent measurement techniques. This chapter looks at Indications; Techniques; and Technical aspects of clinical use of indirect methods.