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The neurological examination
- Authors: Laurent Garosi and Mark Lowrie
- From: BSAVA Manual of Canine and Feline Neurology
- Item: Chapter 1, pp 1 - 24
- DOI: 10.22233/9781910443125.1
- Copyright: © 2013 British Small Animal Veterinary Association
- Publication Date: January 2013
Abstract
The neurological evaluation of a patient aims to determine the anatomical diagnosis (location and distribution of the lesion within the nervous system) together with the patient’s signalment and history in order to determine the differential diagnosis. Disease severity can help the clinician to determine the eventual prognosis of the conditions considered in the differential diagnosis. This chapter looks at history, general physical examination, neurological examination, part I: hands-off examination, part II: hands-on examination. This chapter includes 28 video clips.
The neurological examination, Page 1 of 1
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Bilateral vestibular disease
This clip shows a cat with bilateral vestibular syndrome. A wide excursion of the head is seen from side to side in combination with falling to both sides. This cat had bilateral otitis media/interna. (See page 16 in the Manual)
Cerebellar ataxia
This clip shows a dog with cerebellar ataxia. Note the marked hypermetric gait in all four limbs as well as head incoordination. It is important to note that this dog is not showing any signs of paresis, which is consistent with generalized truncal and head ataxia as a result of a cerebellar lesion. (See page 7 in the Manual)
Corneal reflex
The corneal reflex is elicited by touching the cornea and observing for closure of the eyelids. The afferent arm of this reflex is mediated by the corneal branch of the trigeminal nerve (CN V; corneal sensation), whilst the efferent arm is mediated by the facial nerve (CN VII; closure of the eyelid). (See pages 12, 13 and 14 in the Manual)
Cranial tibial reflex
The cranial tibial reflex is elicited by hitting the proximal cranial tibial muscle and observing a reflex flexion of the tarsus. This reflex evaluates the integrity of spinal cord segments L6–S1 and associated nerve roots, as well as the peroneal peripheral nerve. (See page 22 in the Manual)
Cutaneous trunci reflex
The cutaneous trunci reflex is elicited by pinching the skin over the lumbar spine with forceps. It is tested from caudal to cranial on each side of the spine, starting at the level of the wings of ilium and continuing cranially to the level of T2. Bilateral contraction of the cutaneous trunci muscle indicates a normal reflex. (See page 23 in the Manual)
Dysmetria
This clip shows the ‘two-engine gait’ seen with caudal cervical spinal cord lesions. The gait reveals hypometria in the thoracic limbs and hypermetria in the pelvic limbs. This dog has disc-associated cervical spondylomyelopathy at C6–C7. (See page 7 in the Manual)
Extensor postural thrusting
Extensor postural thrusting is tested by lifting the thoracic limbs off the ground and then lowering the pelvic limbs toward the floor, observing for extension of these limbs and backward steps on touching the surface. (See page 18 in the Manual)
Gag/swallow reflex
The gag/swallow reflex is elicited by applying external pressure to the hyoid bones to stimulate swallowing or by stimulating the pharynx with a finger. It assess the integrity of the glossopharyngeal (CN IX) and vagus (CN X) nerves. (See page 16 in the Manual)
Gastrocnemius reflex
The gastrocnemius reflex is elicited by placing a finger over the gastrocnemius muscle and striking it with a reflex hammer. The normal reaction is extension of the hock. This reflex tests the integrity of spinal cord segments L7–S1 and associated nerve roots, as well as the tibial peripheral nerve. (See page 22 in the Manual)
General proprioceptive ataxia
Cavalier King Charles Spaniel showing general proprioceptive ataxia and upper motor neuron (UMN) paresis in both pelvic limbs as a result of intervertebral disc herniation at T12–T13. (See page 7 in the Manual)
Hemi-walking
Hemi-walking tests the ability of the animal to walk on the thoracic and pelvic limbs on one side whilst holding the limbs on the other side. The animal should be pushed away from the side on which its limbs are supported. The speed and coordination of the movements should be assessed. (See pages 17 and 18 in the Manual)
Hopping
The hopping response is tested by holding the contralateral limb off the ground and supporting the hind end of the animal (or front end if testing a pelvic limb) to put the majority of the bodyweight on the limb being tested. The animal is then pushed laterally on the side of the limb being tested. The normal response is hopping on the limb being tested to accommodate a new body position as the centre of gravity is displaced laterally. An equal response should be seen on both sides. (See page 18 in the Manual)
Lip pinch
This reflex is tested by pinching the lip and observing lip contracture. Both sides must be assessed to evaluate possible asymmetry. The afferent arm of this reflex involves the trigeminal nerve (CN V), whilst the efferent arm involves the facial nerve (CN VII). (See page 12 in the Manual)
Menace response
A mixed-breed dog is seen to have increased extensor tone in all limbs following stimulation. There is no change in mentation seen with this extensor rigidity, indicating normal brain function and is more compatible with a neuromuscular lesion. (See page 8 in the Manual)
Myotonia
A mixed-breed dog is seen to have increased extensor tone in all limbs following stimulation. There is no change in mentation seen with this extensor rigidity, indicating normal brain function and is more compatible with a neuromuscular lesion. (See page 8 in the Manual)
Nasal stimulation
The response to nasal stimulation is a cortically mediated withdrawal of the head. The afferent arm of this reflex is mediated by the trigeminal nerve (CN V). The integration of this response occurs in the contralateral forebrain. Both sides should be carefully assessed to evaluate possible asymmetry. (See page 12 in the Manual)
Nociception response
Deep pain perception (nociception) is tested by pinching the digits with the fingers or haemostats. A behavioural response to this noxious stimulus (turning of the head, vocalization, attempting to bite) is considered as evidence of conscious pain perception. (See page 23 in the Manual)
Palpebral reflex
The palpebral is elicited by touching the medial or lateral canthus of the eye and observing for closure of the eyelids. The afferent arm of this reflex is mediated by the trigeminal nerve (CN V; facial stimulation), whilst the efferent arm is mediated by the facial nerve (CN VII; closure of the eyelids). (See page 12 in the Manual)
Paradoxical vestibular disease
This clip shows a dog with hypermetria in the right thoracic and pelvic limbs with no evidence of paresis. A subtle left-sided head tilt is visible. This combination of clinical signs is suggestive of a central vestibular syndrome on the right side, causing a paradoxical head tilt. A mass lesion was found in the right cerebellar-medullary angle. (See page 15 in the Manual)
Patellar reflex
The patellar reflex is performed with the animal placed lateral recumbency and the stifle slightly flexed. The tested limb is supported by placing one hand under the thigh. The reflex is elicited by hitting the patellar ligament with a reflex hammer and observing an extension of the stifle joint (reflex contraction of the quadriceps femoris muscle). This reflex evaluates the integrity of spinal cord segments L4–L6 and associated nerve roots, as well as the femoral nerve. (See page 21 in the Manual)
Perineal reflex
The perineal reflex is elicited by stimulating the perineum with a haemostat, which causes a reflex contraction of the anal sphincter and flexion of the tail. This reflex tests the integrity of the caudal nerves of the tail, the pudental nerve, spinal cord segments S1–Cd5 and associated nerve roots. (See page 22 in the Manual)
Physiological nystagmus
A physiological nystagmus can be induced by moving the head from side to side. The nystagmus is always observed in the plane of rotation of the head and consists of a slow phase away from the direction of the head and a fast phase in the same direction as the head rotation. (See pages 10, 11, 13 and 15 in the Manual)
Proprioceptive placing
Proprioceptive placing of each limb is performed individually. It is essential to fully support the animal and turn the digits of the limb over on to the cranial surface. An immediate response of turning the paw back over and placing the foot on to the floor is considered normal. An absent or delayed response, or a partial return of the digits back to a normal position, is considered abnormal. (See pages 17 and 18 in the Manual)
Pupillary light reflex
The pupillary light reflex (PLR) is tested by shining a bright light into the pupil and assessing for pupillary constriction (direct reflex). The opposite pupil should constrict at the same time (consensual or indirect reflex). A slight dilation usually follows the initial pupillary constriction (pupillary escape) as a consequence of light adaption of photoreceptors. (See page 10 in the Manual)
Vestibular ataxia
This dog has a left-sided head tilt and is leaning/falling to the left. This is consistent with a vestibular ataxia. (See page 7 in the Manual)
Wheelbarrowing
This is a postural reaction test of the forelimbs. It is performed with the neck extended and the pelvic limbs elevated from the ground (with the animal supported under the abdomen). The animal is then forced to walk forwards. (See page 18 in the Manual)
Withdrawal reflex: pelvic limb
The withdrawal reflex is tested by pinching the nail bed or digit of the pelvic limb with fingers or haemostats. The stimulus causes a reflex contraction of the flexor muscles and withdrawal of the limb being tested. A normal withdrawal reflex implies flexion of the hock, stifle and hip. Whilst the withdrawal reflex is evoked, the contralateral limb should be observed for reflex extension. (See page 20 in the Manual)
Withdrawal reflex: thoracic limb
The withdrawal reflex is tested by pinching the nail bed or digit of the thoracic limb with fingers or haemostats. The stimulus causes a reflex contraction of the flexor muscles and withdrawal of the limb being tested. A normal withdrawal reflex implies flexion of the carpus, elbow and shoulder. (See page 19 in the Manual)